PXD071007 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Pseudomonas aeruginosa LasI/RhlI quorum sensing system controls protease-mediated autoaggregation behavior, cell envelope characteristics and extracellular proteome responses |
| Description | Description Using Pseudomonas aeruginosa PA14 bacterial strain, we determined the contribution of the master regulator LasI/RhlI of Quorum sensing system (QS) to extracellular proteome responses quantitative mass spectrometry-based proteomics and bioinformatics. The LasI/RhlI QS system perturbed the extracellular abundance of a total of 545 extracellular proteins during late exponential and early stationary growth phases. We allocated most of these differentially expressed proteins to the following large functional groups: metabolism; transcription and translation; transport and secretion systems; cell envelope integrity; redox processes; invasiveness and toxicity; and motility. Remarkably, about 95% of the extracellular proteome was upregulated in the lasI-/rhlI- mutant in comparison to the wild type and returned to wild type-status when AHL was added. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-12-03 |
| AnnouncementXML | Submission_2025-12-03_07:49:34.191.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Elena Vikström |
| SpeciesList | scientific name: Pseudomonas aeruginosa PA14; NCBI TaxID: NEWT:652611; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-11-20 13:14:18 | ID requested | |
| ⏵ 1 | 2025-12-03 07:49:34 | announced | |
Publication List
Keyword List
| submitter keyword: Pseudomonas aeruginosa PA14 |
Contact List
| Elena Vikström |
|---|
| contact affiliation | Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Sweden |
| contact email | elena.vikstrom@liu.se |
| lab head | |
| Elena Vikström |
|---|
| contact affiliation | Linköping University |
| contact email | elena.vikstrom@liu.se |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD071007
- Label: PRIDE project
- Name: Pseudomonas aeruginosa LasI/RhlI quorum sensing system controls protease-mediated autoaggregation behavior, cell envelope characteristics and extracellular proteome responses
