PXD070994 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | ARPE-19 human cell lines (Small Extracellular Vesicles, early and late endosomes) |
| Description | LAMP2A affects endosomal biology, including the degradation and exosome pathways. Findings reveal how LAMP2A influences endosomal maturation, protein composition, and communication potential, linking its decline in aging to impaired cellular clearance and tissue homeostasis. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-19 |
| AnnouncementXML | Submission_2026-01-18_16:51:12.092.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Rune Matthiesen |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue; acetylated residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-11-20 08:04:06 | ID requested | |
| ⏵ 1 | 2026-01-18 16:51:13 | announced | |
Publication List
| 10.1016/j.isci.2025.114305; |
| Ferreira JV, Ferraz LC, da Rosa Soares A, Ejtehadifar M, Carvalho AS, Hall MJ, Morello J, Beck HC, Ramalho JS, Matthiesen R, Pereira P, LAMP2A regulates endosomal protein composition and membrane identity in exosome biogenesis. iScience, 29(1):114305(2026) [pubmed] |
Keyword List
Contact List
| Rune Matthiesen |
|---|
| contact affiliation | NMS Research, Lisbon |
| contact email | runem2009@gmail.com |
| lab head | |
| Rune Matthiesen |
|---|
| contact affiliation | Computational and Experimental Biology Group, CEDOC
NOVA MEDICAL SCHOOL / FACULDADE DE CIÊNCIAS MÉDICAS
UNIVERSIDADE NOVA DE LISBOA
Rua Câmara Pestana, 6-6A | 1150-082 Lisboa
Portugal |
| contact email | runem2009@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD070994 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD070994
- Label: PRIDE project
- Name: ARPE-19 human cell lines (Small Extracellular Vesicles, early and late endosomes)
