PXD070730 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis of FKBP8 knockdown in HEK293T cells |
| Description | To investigate the effects of FKBP8 depletion in HEK293T cells, cells were transfected with siRNA targeting FKBP8 or with a non-targeting control siRNA for 48 hours. After transfection, cells were collected; 10% of the material was used for whole-cell proteome analysis, and the remaining 90% was used for mitochondrial isolation. Both whole-cell and mitochondrial pellets were snap-frozen in liquid nitrogen and subjected to LC-MS/MS proteomic analysis. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-17 |
| AnnouncementXML | Submission_2026-03-17_09:10:20.644.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Remigiusz Serwa |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-11-14 05:48:01 | ID requested | |
| ⏵ 1 | 2026-03-17 09:10:21 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: FK506-binding protein, knockdown,FKBP8, mitochondria, HEK293T |
Contact List
| Agnieszka Chacinska |
|---|
| contact affiliation | IMol Polish Academy of Sciences, Flisa 6, 02-247 Warsaw, Poland |
| contact email | a.chacinska@imol.institute |
| lab head | |
| Remigiusz Serwa |
|---|
| contact affiliation | The International Institute of Molecular Mechanisms and Machines, Polish Academy of Sciences |
| contact email | r.serwa@imol.edu.pl |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD070730 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD070730
- Label: PRIDE project
- Name: Proteomic analysis of FKBP8 knockdown in HEK293T cells
