PXD070697-1

PXD070697 is an original dataset announced via ProteomeXchange.

Title	Proteasome activity maintains cell type-specific gene expression
Description	This project delves into the effects of the loss of the ubiquitin-binding region of the proteasomal component hRPN10, and its downstream effects in processes related to cell identity preservation. Several of these processes are shown to be transcriptionally regulated through the accumulation of proteasome substrate and chromatin-associated deubiquitinase OTUD5
HostingRepository	MassIVE
AnnounceDate	2026-01-09
AnnouncementXML	Submission_2026-01-09_09:09:50.122.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yan Wang
SpeciesList	scientific name: Human;
ModificationList	GG
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-11-13 13:53:45	ID requested
⏵ 1	2026-01-09 09:09:50	announced

no publication

submitter keyword: proteasome, ubiquitin, tissue specificity, cell identity, Rpn10, PSMD4, OTUD5, DatasetType:Proteomics

Yan Wang
contact affiliation	NIH/NIDCR
contact email	wangyan2@nih.gov
lab head
Yan Wang
contact affiliation	NIH
contact email	yan.wang2@nih.gov
dataset submitter

MassIVE dataset URI

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