PXD070528 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Characterization of the Angiosarcoma Microenvironment |
| Description | Angiosarcomas are ultra-rare, highly aggressive sarcomas with limited treatment options and dismal prognosis. In this project, we quantified immune cell infiltrates in the angiosarcoma tumor microenvironment. Unsupervised clustering was applied to reveal prognostically significant immune phenotypes. Proteomic profiling of 88 angiosarcoma samples (54 primary tissue, 17 local relapse tissue, and 17 metastatic tissue), 20 benign control tissues and 9 pooled groups was performed by LC–MS/MS to compare various AS subtypes, as well as up- and downregulated pathways between immune cell clusters. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-14 |
| AnnouncementXML | Submission_2026-03-13_21:46:15.966.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Proteomics Facility |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | timsTOF Pro 2 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-11-10 02:17:07 | ID requested | |
| ⏵ 1 | 2026-03-13 21:46:16 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Sarcoma, angiosarcoma, tumor immune environment, tumor microenvironment |
Contact List
| Prof. Dr. Alexander Quaas |
|---|
| contact affiliation | Institute of Pathology, University Hospital Cologne, Cologne, Germany |
| contact email | alexander.quaas@uk-koeln.de |
| lab head | |
| Proteomics Facility |
|---|
| contact affiliation | CECAD Research Center |
| contact email | proteomics-facility@uni-koeln.de |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD070528 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD070528
- Label: PRIDE project
- Name: Characterization of the Angiosarcoma Microenvironment
