⮝ Full datasets listing
PXD070331-1
PXD070331 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Plasma Multi-Omics in Response to Long-Term Low-Dose Ionizing Radiation |
| Description | This study performed quantitative plasma proteomics on 5 radiation-exposed workers and 5 healthy controls using high-resolution LC-MS/MS (Orbitrap Exploris 480). Proteins were extracted, reduced, alkylated, trypsin-digested, and analyzed in DDA mode. Data was processed with Spectronaut 14 using dynamic iRT prediction, 1% FDR filtering, and top3 peptide quantification. Differentially expressed proteins between groups were identified using Welch's ANOVA (p<0.05, FC>1.5) to investigate the impact of occupational radiation exposure. |
| HostingRepository | iProX |
| AnnounceDate | 2025-11-05 |
| AnnouncementXML | Submission_2025-11-04_17:51:15.287.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zhongwei Chang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-11-04 17:50:38 | ID requested | |
| ⏵ 1 | 2025-11-04 17:51:15 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Ionizing radiation, Metabolomics, Lipidomics, Proteomics, Co-occurrence network |
Contact List
| Xinjun Wang | |
|---|---|
| contact affiliation | Affiliated Suzhou Hospital ofNanjing Medical University, Suzhou Municipal Hospital |
| contact email | xjwang16@fudan.edu.cn |
| lab head | |
| Zhongwei Chang | |
| contact affiliation | Huaihe Hospital of Henan University |
| contact email | 2628177895@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
