PXD070247 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomics data for "A single-amino-acid cleavage controls global mitochondrial complex integrity" |
| Description | Mitochondrial proteostasis depends on precise N-terminal processing of imported precursor proteins, and defects in this maturation step are implicated in severe human diseases, yet the functional impact in humans remain unclear. This dataset analysis quantiative changes in the proteome of mitochondria isolated from HEK293T cells, and HEK293T cells lacking the aminopeptidase ICP55 |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-01 |
| AnnouncementXML | Submission_2026-08-01_04:07:30.609.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Pitter Huesgen |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | impact II |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-11-03 13:53:29 | ID requested | |
| ⏵ 1 | 2026-08-01 04:07:31 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: N-terminome,Mitochondria, protein complex stability, respiratory chain, Proteomics |
Contact List
| Prof. Dr. Pitter Huesgen |
|---|
| contact affiliation | University of Freiburg Faculty of Biology Biochemistry and Functional Proteomics Schänzlestrasse 1 79104 Freiburg Germany |
| contact email | pitter.huesgen@biologie.uni-freiburg.de |
| lab head | |
| Pitter Huesgen |
|---|
| contact affiliation | University of Freiburg
Faculty of Biology
Biochemistry and Functional Proteomics |
| contact email | pitter.huesgen@biologie.uni-freiburg.de |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD070247 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD070247
- Label: PRIDE project
- Name: Proteomics data for "A single-amino-acid cleavage controls global mitochondrial complex integrity"
