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PXD070232-1

PXD070232 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleExploring Proteomic Differences in PBMCs for Sex-Specific Insights into Alzheimer’s Disease
DescriptionThis study investigated sex-dependent proteomic alterations in peripheral blood mononuclear cells (PBMCs) from Alzheimer’s disease (AD) patients. Quantitative DIA-based proteomics revealed both shared and sex-specific pathways, including complement activation, coagulation, and metabolic processes. These findings highlight systemic immune and metabolic remodeling in AD that differ between males and females.
HostingRepositoryPRIDE
AnnounceDate2026-01-15
AnnouncementXMLSubmission_2026-01-15_10:17:22.310.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD070232
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterTakako Takaku
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-11-03 09:23:20ID requested
12026-01-15 10:17:22announced
Publication List
10.6019/PXD070232;
10.17912/MICROPUB.BIOLOGY.001922;
Keyword List
submitter keyword: None
Contact List
Colin K.
contact affiliationDepartment of Biomedical Sciences, University of North Dakota, Grand Forks, ND, USA
contact emailcolin.combs@und.edu
lab head
Takako Takaku
contact affiliationDepartment of Biomedical Sciences, University of North Dakota, Grand Forks, ND, USA
contact emailtakako.takaku@und.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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