PXD070119 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteome of Coxsackievirus B3 infection models of human enterocyte cells |
| Description | Coxsackieviruses B (CVBs) emerge as candidate environmental triggers for the autoimmunity against pancreatic islet β cells leading to type 1 diabetes. Persistent CVB infections in the gut and pancreas correlate with islet autoantibody seroconversion, suggesting defective antiviral control in predisposed individuals. Recent antiviral and vaccine trials underscore the need to define immune mechanisms at the intestinal entry site. To address this, we investigated how CVB3 modulates antigen presentation in enterocytes and antigen-presenting cells by using immunopeptidomics and proteomics, and how these events shape downstream T-cell immunity. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-07 |
| AnnouncementXML | Submission_2026-05-07_03:43:09.547.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Nicola Ternette |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-30 16:24:21 | ID requested | |
| ⏵ 1 | 2026-05-07 03:43:10 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project |
| submitter keyword: Coxsackievirus B,autoimmunity, human leukocyte antigen (HLA), intestinal immunity, type 1 diabetes |
Contact List
| Nicola Ternette |
|---|
| contact affiliation | University of Oxford University of Dundee |
| contact email | nicola.ternette@ndm.ox.ac.uk |
| lab head | |
| Nicola Ternette |
|---|
| contact affiliation | University of Oxford |
| contact email | nicola.ternette@ndm.ox.ac.uk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD070119 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD070119
- Label: PRIDE project
- Name: Proteome of Coxsackievirus B3 infection models of human enterocyte cells
