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PXD070057-1

PXD070057 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic Analysis of the impact of uric acid pretreatment on APAP-treated mouse primary hepatocytes
DescriptionThis study investigates the effect of uric acid (UA) pretreatment on protein expression profiles in acetaminophen (APAP)-induced hepatotoxicity. Primary mouse hepatocytes were divided into two groups: APAP and UA+APAP. Cells in the UA+APAP group were pretreated with 400 μM UA for 2 hours, followed by 5 mM APAP treatment for 6 hours. After treatment, proteins were extracted and analyzed using LC-MS/MS-based proteomics.
HostingRepositoryiProX
AnnounceDate2025-10-29
AnnouncementXMLSubmission_2025-10-29_20:09:10.784.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRong Wu
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-29 20:08:56ID requested
12025-10-29 20:09:11announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: APAP, uric acid, hepatocyte
Contact List
Shenhai Gong
contact affiliationSouthern Medical University
contact emailgsh0526@smu.edu.cn
lab head
Rong Wu
contact affiliationSouthern Medical University
contact emailwrong1995@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI