PXD069989 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | 4D label-free quantitative proteomics of 32 leukemia patient samples |
| Description | Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is a high-risk T-ALL subtype with distinct immunophenotypes and genetic alterations, complicating diagnosis and treatment. Although cytogenetic and gene expression studies have advanced the diagnostic and therapeutic strategies, the proteomics signatures of ETP-ALL remain underexplored. Herein, we performed 4D label-free proteomic analyses on mononuclear cells isolated from ETP-ALL, T-ALL, acute myeloid leukemia (AML), and healthy donor samples to identify molecular signatures specific to ETP-ALL. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-12-30 |
| AnnouncementXML | Submission_2025-12-29_23:03:16.600.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Feng Xian |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro 2 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-28 10:08:21 | ID requested | |
| ⏵ 1 | 2025-12-29 23:03:17 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: 4D, leukemia, patient samples, label-free, quantitative proteomics |
Contact List
| Yinghui Zhu |
|---|
| contact affiliation | School of Life Sciences and Technology, Tongji University, Shanghai, China |
| contact email | zhuyinghui@tongji.edu.cn |
| lab head | |
| Feng Xian |
|---|
| contact affiliation | Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna |
| contact email | feng.xian@univie.ac.at |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD069989 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069989
- Label: PRIDE project
- Name: 4D label-free quantitative proteomics of 32 leukemia patient samples
