PXD069904-1

PXD069904 is an original dataset announced via ProteomeXchange.

Title	Secretome analysis of primary CLL cells
Description	Secretome analysis of primary CLL cells co-cultured in serum-free IMDM medium with either EL08 stroma cells or YK6 follicular dendritic cells overexpressing CD40L and interleukin 21 (“FDC CD40L IL21”).
HostingRepository	PRIDE
AnnounceDate	2026-01-22
AnnouncementXML	Submission_2026-01-22_06:21:29.475.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Piero Giansanti
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-10-25 14:49:58	ID requested
⏵ 1	2026-01-22 06:21:30	announced

Sober, ó, n V, Osswald L, Moore A, Sosnowska D, Swinerd G, Chen J, Bayg, ü, n S, Diehl C, Seyhan G, Kraus L, G, ö, lling V, Trapp R, O'Neill TJ, Bortoluzzi S, Kovacs D, Ammon T, Singroul P, Hubarzhevska Y, Ö, llinger R, Mueller S, Baranov O, Giansanti P, Gillhuber F, Grath S, Weigert O, Rosenwald A, Sasaki Y, Rajewsky K, Steiger K, Bassermann F, Rad R, Krappmann D, Ringshausen I, Schmidt-Supprian M, B signaling in B cells drives SLL/CLL-like lymphomagenesis and overcomes microenvironmental dependencies. Leukemia, 40(3):522-539(2026) [pubmed]

10.1038/s41375-025-02844-8;

submitter keyword: leukemia, DIA,Proteomics, secretome

Piero Giansanti
contact affiliation	Bavarian Center for Biomolecular Mass Spectrometry at Klinikum rechts der Isar Technical University of Munich
contact email	piero.giansanti@tum.de
lab head
Piero Giansanti
contact affiliation	Technical University of Munich
contact email	piero.giansanti@tum.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD069904

PRIDE project URI

• PRIDE
  1. PXD069904
     1. Label: PRIDE project
     2. Name: Secretome analysis of primary CLL cells