PXD069873-1

PXD069873 is an original dataset announced via ProteomeXchange.

Title	ZmbZIP39 coordinates source-flow-sink relations to boost grain filling in maize
Description	The orchestration of source, flow, and sink is fundamental to efficient grain filling in maize, yet the regulatory network synchronizing these processes remains a major enigma. To identify key regulators, we used the sucrose transporter ZmSUT1, a critical component of the ‘flow’ pathway, as a molecular target. This approach led to the discovery of ZmbZIP39 that acts as a central coordinator of grain filling. We demonstrate that ZmbZIP39 governs the entire process by simultaneously regulating photosynthesis (source), sucrose transport (flow), and sucrose metabolism and nutrient storage (sink). Mechanistically, ZmbZIP39 directly activates the expression of ZmSUT1 and ZmSUT7, facilitating sucrose loading and long-distance transport from leaves to developing kernels. It also promotes sucrose cleavage by directly upregulating three sucrose synthase-encoding genes. Furthermore, ZmbZIP39 directly controls the expression of the zein-encoding genes and endosperm-filling hub Opaque2, thereby driving nutrient storage and endosperm development. ZmbZIP39 also functions within a higher-order regulatory complex, synergizing with key factors like ZmABI19, ZmbZIP29, OHP1, OHP2, and ZmNAC130, to amplify their collective impact. ZmbZIP39-mediated regulatory capacity is further enhanced by its autoactivation activity, creating a positive feedback loop that robustly strengthens its downstream network. Our findings establish ZmbZIP39 as a master regulator that optimizes source-flow-sink relations.¬
HostingRepository	iProX
AnnounceDate	2025-10-24
AnnouncementXML	Submission_2025-10-24_02:22:11.912.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tao Yang
SpeciesList	scientific name: Zea mays; NCBI TaxID: 4577;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-10-24 02:21:50	ID requested
⏵ 1	2025-10-24 02:22:12	announced

Dataset with its publication pending

submitter keyword: Maize, source, flow, sink, ZmbZIP39, grain filling

Tao Yang
contact affiliation	Sichuan Agricultural University
contact email	13212799561@163.com
lab head
Tao Yang
contact affiliation	Sichuan Agricultural University
contact email	13212799561@163.com
dataset submitter

iProX dataset URI