PXD069845 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Establishing a phosphoproteome for ovarian carcinoma histotypes |
| Description | Ovarian cancer is the eight most common cancer in the women and the deadliest gynecologic malignancy. The majority of patients (90%) are diagnosed with epithelial ovarian cancer (EOC), which is comprised by five main histotypes – high-grade serous ovarian carcinoma (HGSC), low-grade serous ovarian carcinoma (LGSC), endometrioid ovarian carcinoma (EC), mucinous ovarian carcinoma (MC), and clear cell ovarian carcinoma (CCC). The established diagnostic biomarker CA-125 is unspecific and has been shown to not be suitable for early detection. Due to limited diagnostic tools and EOC being asymptomatic in early stages (I-II), 70% of patients are diagnosed in late stages (III-IV) and therefore the disease is associated with poor prognosis. Although the histotypes have distinct clinicopathologic characteristics, first line treatment has remained the same the last four decades regardless of histotype. In this study, we aimed to profile the phosphorylated proteins of primary tumors from a cohort of 180 EOC patients comprising HGSC, EC, MC, and CCC across all stages. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-20 |
| AnnouncementXML | Submission_2026-08-19_22:38:27.242.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Lucas Werner |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-23 14:22:00 | ID requested | |
| ⏵ 1 | 2026-08-19 22:38:28 | announced | |
Publication List
Keyword List
| submitter keyword: histotypes, late-stage, early-stage, carcinoma,Ovarian, phosphoproteomics, LC-MS/MS |
Contact List
| Khalil Helou |
|---|
| contact affiliation | Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg |
| contact email | khalil.helou@oncology.gu.se |
| lab head | |
| Lucas Werner |
|---|
| contact affiliation | University of Gothenburg |
| contact email | lucas.werner@gu.se |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD069845 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069845
- Label: PRIDE project
- Name: Establishing a phosphoproteome for ovarian carcinoma histotypes
