PXD069824 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The TORC1-regulated quiescence trajectory is shaped by an Rts3-dependent feedback mechanism that limits Sit4/PP6 phosphatase activity |
| Description | Four sets of MS-based proteomics experiments were performed: (1) Serine/Threonine protein phosphatases were profiled by microcystin-LR (MCLR)-based enrichment in different growth conditions; (2) TurboID-RTS3-based proximity labeling was performed to characterize the RTS3 protein neighborhood; (3) A global phosphoproteome was acquired to identify Rts3-regulated phosphosites, measuring both enriched phosphopetides and FT to determine protein abundances; (4) Expression proteomics of WT, sit4delta, rts3delta and sit4delta/rts3delta cells in different growth conditions to determine the role of Sit4 and Rts3 in regulating protein abundances. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-31 |
| AnnouncementXML | Submission_2026-01-31_00:54:27.326.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Michael Stumpe |
| SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: NEWT:4932; |
| ModificationList | phosphorylated residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-23 06:17:50 | ID requested | |
| ⏵ 1 | 2026-01-31 00:54:27 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: LC-MSMS,Yeast, Saccharomyces cerevisiae, phosphatase, phosphoproteomics |
Contact List
| Joern Dengjel |
|---|
| contact affiliation | Dept. of Biology University of Fribourg Chemin du Musee 10 1700 Fribourg Switzerland |
| contact email | joern.dengjel@unifr.ch |
| lab head | |
| Michael Stumpe |
|---|
| contact affiliation | Department of Biology,
University of Fribourg |
| contact email | michael.stumpe@unifr.ch |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD069824 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069824
- Label: PRIDE project
- Name: The TORC1-regulated quiescence trajectory is shaped by an Rts3-dependent feedback mechanism that limits Sit4/PP6 phosphatase activity
