PXD069742 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Targeting Fibrotic Scars with Extracellular Vesicles Extracted from Mature Aloe vera: Enhanced Antioxidant, Anti-inflammatory, and Antifibrotic Activity through M2 Macrophage Polarization and Myofibroblasts Inhibition. |
| Description | This study aimed to isolate and characterize Av-EVs and evaluate their antioxidant, anti-inflammatory, and antifibrotic properties in vitro, focusing on the impact of extraction method and plant maturity. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-25 |
| AnnouncementXML | Submission_2026-05-24_16:51:49.879.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Stefan Schulze |
| SpeciesList | scientific name: Aloe vera; NCBI TaxID: NEWT:34199; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-21 13:17:23 | ID requested | |
| ⏵ 1 | 2026-05-24 16:51:50 | announced | |
Publication List
| 10.21769/bioprotoc.5664; |
| Ceballos-Santa CM, Sanchez-Ortiz I, Gaborski TR, Wuertz-Kozak K, -Derived Extracellular Vesicles via Manual and Shear-Force Homogenization. Bio Protoc, 16(8):e5664(2026) [pubmed] |
Keyword List
| submitter keyword: inflammation resolution, myofibroblast differentiation,Wound healing, oxidative stress, regenerative skin therapy. |
Contact List
| Karin Wuertz-Kozak |
|---|
| contact affiliation | Department of Biomedical Engineering, Rochester Institute of Technology, Rochester, USA |
| contact email | kwbme@rit.edu |
| lab head | |
| Stefan Schulze |
|---|
| contact affiliation | Rochester Institute of Technology |
| contact email | sschulze@sas.upenn.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD069742 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069742
- Label: PRIDE project
- Name: Targeting Fibrotic Scars with Extracellular Vesicles Extracted from Mature Aloe vera: Enhanced Antioxidant, Anti-inflammatory, and Antifibrotic Activity through M2 Macrophage Polarization and Myofibroblasts Inhibition.
