PXD069555-1

PXD069555 is an original dataset announced via ProteomeXchange.

Title	RHOT proteins link mitochondrial motility to cardiomyocyte sarcomere maturation.
Description	Proteome and phosphoproteome analysis of left ventricular tissue obtained from mice with embryonic, cardiomyocyte-selective deletion of Rhot1/2 (cRhot1/2-KO) and controls (cRhot1/2-Con) at 1-day and 4-weeks of age.
HostingRepository	PRIDE
AnnounceDate	2026-04-30
AnnouncementXML	Submission_2026-04-30_04:30:23.464.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Felix Polten
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-10-16 15:03:01	ID requested
⏵ 1	2026-04-30 04:30:24	announced

Froese N, Shymotiuk I, Froese A, Polten F, Jablinski J, Scholz T, Korf-Klingebiel M, Werlein C, Galuppo P, Gigina A, Wihler K, Schneider J, Erschow S, Heimerl M, Szaroszyk M, Hegermann J, Wrede C, Schweitzer T, Pich A, Geffers R, Ricke-Hoch M, K, ü, hnel MP, Jonigk DD, Wende AR, Abel ED, Nikolaev VO, Wollert KC, Bauersachs J, Riehle C, RHOT Proteins Link Mitochondrial Motility to Cardiomyocyte Sarcomere Maturation. Circ Res, 138(9):e327297(2026) [pubmed]

10.1161/circresaha.125.327297;

submitter keyword: Rhot1, heart, Rhot2, mouse

Christian Riehle
contact affiliation	Hannover Medical School, Department of Cardiology and Angiology
contact email	riehle.christian@mh-hannover.de
lab head
Felix Polten
contact affiliation	Hanover Medical School - Division of Molecular and Translational Cardiology
contact email	polten.felix@mh-hannover.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD069555

PRIDE project URI

• PRIDE
  1. PXD069555
     1. Label: PRIDE project
     2. Name: RHOT proteins link mitochondrial motility to cardiomyocyte sarcomere maturation.