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PXD069263-1

PXD069263 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCD8+ T cells are primed by cDC1 and exacerbate tau-mediated neurodegeneration
DescriptionMHC-I and MHC-II peptidomes of brain, spleen, and deep cervical lymph nodes (dCLN) from control and P301S tau transgenic 64 mice expressing human APOE4. Data were collected in ddaPASEF mode on a timsTOF Ultra 2.
HostingRepositoryMassIVE
AnnounceDate2026-06-29
AnnouncementXMLSubmission_2026-06-29_13:06:50.940.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterCheryl Lichti
SpeciesList scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationListL-methionine sulfoxide; iodoacetamide - site C
InstrumenttimsTOF Ultra 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-09 15:14:36ID requested
⏵ 12026-06-29 13:06:51announced
Publication List
no publication
Keyword List
submitter keyword: immunopeptidomics, neurodegeneration, tauopathy, brain, dCLN, DatasetType:Proteomics
Contact List
David Holtzman
contact affiliationWashington University School of Medicine in St. Louis
contact emaildholtzman@wustl.edu
lab head
Cheryl Lichti
contact affiliationWashington University in St. Louis
contact emailclichti@wustl.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v11/MSV000099442/

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