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PXD069113-1

PXD069113 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLabel-free quantitative proteomics of human healthy gracilis and diseased rotator cuff tear tendons
DescriptionRotator cuff tears (RCT) are among the most common causes of shoulder dysfunction, frequently leading to chronic pain and impaired muscle performance. To gain deeper insight into the molecular mechanisms underlying this condition, proteomic approaches offer an unbiased means of characterizing global protein expression changes. In this study, we compared the proteomic profiles of healthy gracilis muscle and rotator cuff tear (RCT) tissue using label-free quantitative proteomics, with the aim of identifying differentially expressed proteins that may serve as biomarkers or provide mechanistic insight into disease progression.
HostingRepositoryPRIDE
AnnounceDate2025-11-24
AnnouncementXMLSubmission_2025-11-24_02:26:00.231.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGreta Moschini
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-03 02:38:23ID requested
12025-11-24 02:26:00announced
Publication List
10.1101/2025.02.02.635939;
Keyword List
submitter keyword: Human, LC-MSMS, Tendon
Contact List
Jess Gerrit Snedeker
contact affiliationLaboratory of Orthopedic Biomechanics, ETH Zurich (Department of Health Sciences and Technology) and University of Zurich (Medical Faculty)
contact emailjess.snedeker@hest.ethz.ch
lab head
Greta Moschini
contact affiliationETH Zürich
contact emailgretam@ethz.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
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