PXD069112-1

PXD069112 is an original dataset announced via ProteomeXchange.

Title	Vaspin-induced effects in brown adipocytes – Proteome
Description	To gain insights into cellular responses of brown and white adipoctes to vaspin a proteomic analysis was concucted. Murine brown (imBA) and white (3T3L1) cells were treated with 500 ng/ml vaspin for 6h, 12h and 24h, followed by lysis in RIPA buffer.
HostingRepository	PRIDE
AnnounceDate	2025-12-12
AnnouncementXML	Submission_2025-12-12_02:17:15.054.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD069112
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Kristin Schubert
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-10-03 02:24:16	ID requested
⏵ 1	2025-12-12 02:17:16	announced

10.6019/PXD069112;

Rap, ö, hn I, Broghammer H, Hoffmann A, M, ö, hlis K, Moormann A, Kaczmarek I, Thor D, Gro, ß, kopf H, Krieg L, Karkossa I, Schubert K, von Bergen M, Krause K, Breitfeld J, Kovacs P, Kl, ö, ting N, Nuwayhid R, Langer S, Ghosh A, Wolfrum C, Stumvoll M, Bl, ü, her M, Heiker JT, Weiner J, Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo. Nat Commun, 16(1):11075(2025) [pubmed]

10.1038/s41467-025-66950-y;

submitter keyword: Browning,Adipose tissue, Proteome, Vaspin, DDA

Kristin Schubert
contact affiliation	Department Molecular Toxicology, Helmholtz Centre for Environmental Research GmBH - UFZ
contact email	kristin.schubert@ufz.de
lab head
Kristin Schubert
contact affiliation	Helmholtz-Centre for Environmental Research
contact email	kristin.schubert@ufz.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD069112

PRIDE project URI

• PRIDE
  1. PXD069112
     1. Label: PRIDE project
     2. Name: Vaspin-induced effects in brown adipocytes – Proteome