PXD068965 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | CK2-mediated DEK Phosphorylation Drives PBX3 Overexpression: A Core Event in Hematopoietic Stem Cell-to-Leukemia Stem Cell Transformation |
| Description | 1. LSCs from MLL-AF9-driven DekTg-fl, Tie2-Cre AML mice were sorted, followed by further proteomic assay. 2. To illustrate DEK-interacting proteins, we performed anti-Flag co-immunoprecipitation (co-IP) followed by mass spectrometry using MLL-AF9-driven LSCs to characterize protein interactomes of DEK. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-06 |
| AnnouncementXML | Submission_2026-07-05_23:55:41.794.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | yufei lei |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-09-29 09:33:35 | ID requested | |
| ⏵ 1 | 2026-07-05 23:55:42 | announced | |
Publication List
Keyword List
| submitter keyword: PBX3,DEK, Leukemia stem cells |
Contact List
| Zhe Chen |
|---|
| contact affiliation | Department of Radiological Medicine, School of Basic Medical Sciences, Chongqing Medical University |
| contact email | chenzhe925@cqmu.edu.cn |
| lab head | |
| yufei lei |
|---|
| contact affiliation | Chongqing Medical University |
| contact email | 2019203010037@whu.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD068965 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD068965
- Label: PRIDE project
- Name: CK2-mediated DEK Phosphorylation Drives PBX3 Overexpression: A Core Event in Hematopoietic Stem Cell-to-Leukemia Stem Cell Transformation
