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PXD068932-1

PXD068932 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe H3K27me3 reader UAD-2 recruits a TAF-12-containing transcription machinery to initiate piRNA expression within heterochromatic clusters
DescriptionIn this project, we performed immunoprecipitation (IP) experiments from whole-worm lysates of uad-2::gfp::3xflag animals and identified putative UAD-2-interacting partners through quantitative mass spectrometry (MS). Using FLAG-tagged TAF-12 as bait, we conversely substantiated the interaction between UAD-2 and TAF-12 via the IP-MS method.
HostingRepositoryiProX
AnnounceDate2025-09-28
AnnouncementXMLSubmission_2025-09-29_00:12:46.657.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXinya Huang
SpeciesList scientific name: Caenorhabditis elegans; NCBI TaxID: 6239;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-09-29 00:12:18ID requested
12025-09-29 00:12:47announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: UAD-2, TAF-12, piRNA transcription
Contact List
Shouhong Guang
contact affiliationUniversity of Science and Technology of China
contact emailsguang@ustc.edu.cn
lab head
Xinya Huang
contact affiliationUniversity of Science and Technology of China
contact emailhr1996@mail.ustc.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI