PXD068902-1

PXD068902 is an original dataset announced via ProteomeXchange.

Title	LAPTM4B maintains stemness in acute myeloid leukemia stem cells by promoting SLC7A1-mediated arginine uptake
Description	To investigate the specific molecular mechanisms by which LAPTM4B regulates AML pathogenesis., we performed quantitative proteomic profiling of LSCs from MA9-Laptm4bfl/fl and MA9-Laptm4b-cKO mice
HostingRepository	PRIDE
AnnounceDate	2026-09-03
AnnouncementXML	Submission_2026-09-02_20:33:34.460.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Meixi Peng
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-09-28 02:59:48	ID requested
⏵ 1	2026-09-02 20:33:35	announced

Dataset with its publication pending

submitter keyword: Leukemia Stem Cell, LAPTM4B, Arginine, SLC7A1, Stemness

Meixi Peng
contact affiliation	School of Basic Medical Sciences, Chongqing Medical University, Chongging, China
contact email	191074@cqmu.edu.cn
lab head
Meixi Peng
contact affiliation	Chongqing Medical University
contact email	191074@cqmu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD068902

PRIDE project URI

• PRIDE
  1. PXD068902
     1. Label: PRIDE project
     2. Name: LAPTM4B maintains stemness in acute myeloid leukemia stem cells by promoting SLC7A1-mediated arginine uptake