PXD068806-1

PXD068806 is an original dataset announced via ProteomeXchange.

Title	The role of Rora in Somatic Cell Reprogramming
Description	Uncovering novel factors in induced pluripotent stem cells is of great significance for understanding the molecular mechanisms of cell fate determination and advancing somatic cell reprogramming technology. The applicant has, for the first time, discovered that overexpressing RORA significantly enhances somatic cell reprogramming, suggesting that RORA may be one of the key factors in this process. This project aims to investigate the molecular mechanisms by which RORA promotes reprogramming and, based on these findings, establish a more efficient somatic cell reprogramming system. This research is expected to reveal new reprogramming factors and develop a more efficient somatic cell reprogramming system, thereby providing new insights and perspectives for understanding the molecular mechanisms of somatic cell reprogramming and cell fate transition.
HostingRepository	iProX
AnnounceDate	2025-09-25
AnnouncementXML	Submission_2025-09-24_19:40:56.660.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yusha Li
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-09-24 19:40:29	ID requested
⏵ 1	2025-09-24 19:40:57	announced

Dataset with its publication pending

submitter keyword: Somatic Cell Reprogramming Rora

Jing Liu
contact affiliation	Guangzhou Institute of Biomedicine and Health
contact email	liu_jing@gibh.ac.cn
lab head
Yusha Li
contact affiliation	Guangzhou Institute of Biomedicine and Health
contact email	li_yusha@gibh.ac.cn
dataset submitter

iProX dataset URI