PXD068776-1

PXD068776 is an original dataset announced via ProteomeXchange.

Title	Identification of SNHG26-binding proteins in keloid-derived fibroblasts by RNA pull-down and LC-MS/MS
Description	This study aims to elucidate the mechanism by which the long non-coding RNA SNHG26 promotes fibroblast activation in keloid pathogenesis through interactions with protein partners. Using RNA pull-down coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS), we identified proteins that specifically bind to SNHG26 in primary human keloid-derived fibroblasts. Two independent controls—biotinylated poly(A)25 RNA and a biotinylated random nucleotide sequence—were used to ensure binding specificity. The resulting dataset provides a resource for understanding SNHG26-mediated regulatory mechanisms in fibroblast activation and keloid development.
HostingRepository	PRIDE
AnnounceDate	2026-08-20
AnnouncementXML	Submission_2026-08-19_22:38:26.570.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ling Pan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro 2

Revision	Datetime	Status	ChangeLog Entry
0	2025-09-24 08:37:56	ID requested
⏵ 1	2026-08-19 22:38:27	announced

Dataset with its publication pending

submitter keyword: None

Dongqing Li
contact affiliation	Key Laboratory of Basic and Translational Research on Immune-Mediated Skin Diseases, Chinese Academy of Medical Sciences; Jiangsu Provincial Key Laboratory of Dermatology; Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, 210042 Nanjing, China.
contact email	dongqing.li@pumcderm.cams.cn
lab head
Ling Pan
contact affiliation	Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China
contact email	panling@student.pumc.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD068776

PRIDE project URI

• PRIDE
  1. PXD068776
     1. Label: PRIDE project
     2. Name: Identification of SNHG26-binding proteins in keloid-derived fibroblasts by RNA pull-down and LC-MS/MS