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PXD068671-1

PXD068671 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDefining the cardiac acetylome in type 2 diabetes
DescriptionHere, we aimed to assess the effect of type 2 diabetes on lysine acetylation levels of cardiac muscles. We used human left ventricular samples from human donors with and without diabetes and investigated the acetylome.
HostingRepositoryPRIDE
AnnounceDate2026-03-09
AnnouncementXMLSubmission_2026-03-08_18:50:52.181.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMichael Wierer
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Ascend
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-09-22 02:43:26ID requested
12026-03-08 18:50:53announced
Publication List
Degezelle MM, Chaami C, Lewis CTA, Zhang C, Hessel AL, Rainer PP, Kirk JA, Stokke MK, Seaborne RAE, Ochala J, Destabilization of cardiac myosin acetylation and sequestration with type 2 diabetes mellitus. Cardiovasc Diabetol, 25(1):(2026) [pubmed]
10.1186/s12933-025-03052-5;
Keyword List
submitter keyword: Heart
acetylome
type 2 diabetes
Contact List
Julien Ochala
contact affiliationUniversity of Copenhagen Department of Biomedical Sciences Blegdamsvej 3B København N, DK-2200
contact emailjulien.ochala@sund.ku.dk
lab head
Michael Wierer
contact affiliationProteomics Research Infrastructure, University of Copenhagen
contact emailmichael.wierer@sund.ku.dk
dataset submitter
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Dataset FTP location
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