PXD068559-1

PXD068559 is an original dataset announced via ProteomeXchange.

Title	Eurasian common shrew liver proteome over the seasons LC-MSMS
Description	Eurasian common shrews (Sorex araneus) maintain exceptionally high metabolic rates year-round, posing a significant energetic challenge during winter when food availability declines. To investigate seasonal metabolic regulation, we performed proteomic profiling of liver tissue—central to energy homeostasis—across seasons, using a bottom-up/shotgun DDA LC-MSMS proteomics analytical strategy. This approach reveals molecular adaptations that support metabolic resilience and highlights key regulatory shifts in response to environmental stress. The files and search results are labelled as: Liver___G_Juvanile/Adult_Mouse#1-5 Example: “Liver_2020_07_G_J2” is a liver sample collected in 2020 month 07 from juvenile mouse #2 Liver_2020_07_G_J1-5: summer 2020 Liver_2020_11_G_J1-4: fall 2020 Liver_2021_04_G_A1-5: spring 2021 Liver_2021_06_G_A1-5: summer 2021 By exploring these mechanisms, we offer novel insights into the interplay between metabolism, size, and longevity, shedding light on both the wintering strategy of the common shrew and broader mammalian physiology.
HostingRepository	PRIDE
AnnounceDate	2025-10-31
AnnouncementXML	Submission_2025-10-31_02:29:14.641.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD068559
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Tue Bjerg Bennike
SpeciesList	scientific name: Sorex araneus; NCBI TaxID: NEWT:42254;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-09-19 03:38:45	ID requested
⏵ 1	2025-10-31 02:29:15	announced

10.6019/PXD068559;

submitter keyword: LC-MSMS,Sorex araneus, timeseries, liver, seasons, hibernation, shrew

Tue Bjerg Bennike
contact affiliation	Department of Health Science and Technology, The Faculty of Medicine, Aalborg University, Denmark
contact email	tbe@hst.aau.dk
lab head
Tue Bjerg Bennike
contact affiliation	Aalborg University
contact email	tbe@hst.aau.dk
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD068559
     1. Label: PRIDE project
     2. Name: Eurasian common shrew liver proteome over the seasons LC-MSMS