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PXD068530-1

PXD068530 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCalcitriol-Driven IL-10 IL-22 ILC Differentiation from ILCPs
DescriptionCalcitriol, the active metabolite of vitamin D, modulates immune responses via vitamin D receptor (VDR)-dependent signaling, but its role in innate lymphoid cell (ILC) development remains underexplored. This study elucidates the mechanisms by which calcitriol promotes the differentiation and migration of IL-10+IL-22+ ILC3s from ILC progenitors (ILCPs) in murine and human systems, with implications for intestinal inflammatory disorders.
HostingRepositoryPRIDE
AnnounceDate2026-07-14
AnnouncementXMLSubmission_2026-07-14_02:32:45.580.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterQingyang Liu
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-09-19 01:42:37ID requested
12026-07-14 02:32:46announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: ILC, calcitriol, ILCP, differentiation
Contact List
Qingyang Liu
contact affiliationNational Medical Metabolomics International Collaborative Research Center, Central South University, Changsha, Hunan, China
contact email408880@csu.edu.cn
lab head
Qingyang Liu
contact affiliationCentral South University
contact email408880@csu.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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