PXD068391-1

PXD068391 is an original dataset announced via ProteomeXchange.

Title	Crosslinking MS of Separase-Securin-PP2A_A/B/C
Description	Separase-Securin complex with Protein Phospatase 2A (A/B/C) has been crosslinked using by Sulfo-SDA crosslinker.
HostingRepository	PRIDE
AnnounceDate	2026-04-09
AnnouncementXML	Submission_2026-04-09_07:22:17.935.xml
DigitalObjectIdentifier	https://doi.org/10.6019/PXD068391
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Kitaik Lee
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	L-methionine sulfoxide; S-carboxamidoethyl-L-cysteine; 2-pyrrolidone-5-carboxylic acid (Gln); deamidated L-asparagine
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2025-09-15 11:05:15	ID requested
⏵ 1	2026-04-09 07:22:18	announced

10.1126/SCIADV.ADY9807;

10.6019/PXD068391;

submitter keyword: Human

Francis J.O'Reilly
contact affiliation	Center for Structural Biology, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health, Frederick, MD 21702-1201, USA
contact email	oreillyfj@nih.gov
lab head
Kitaik Lee
contact affiliation	Center of Excellence for Data Driven Discovery, Department of Structural Biology, St Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States
contact email	kitaik.lee@stjude.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD068391

PRIDE project URI

• PRIDE
  1. PXD068391
     1. Label: PRIDE project
     2. Name: Crosslinking MS of Separase-Securin-PP2A_A/B/C