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PXD068266-1

PXD068266 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThyroid cancer ATC-PDTC-PTC-N FFPE 4D-DIA proteomics
DescriptionWe performed 4D-DIA proteomic profiling on formalin-fixed paraffin-embedded (FFPE) thyroid tissues, covering anaplastic thyroid carcinoma (ATC), poorly differentiated thyroid carcinoma (PDTC), papillary thyroid carcinoma (PTC), and matched normal (N) controls. Using the timsTOF Pro platform with ion mobility–enhanced DIA, we systematically quantified global protein expression across tumor subtypes. The dataset provides high-quality spectral data and processed protein quantitation matrices, enabling comparative analyses of thyroid cancer progression from differentiated to undifferentiated states. This resource supports biomarker discovery and mechanistic exploration in thyroid cancer biology.
HostingRepositoryiProX
AnnounceDate2025-09-10
AnnouncementXMLSubmission_2025-09-29_18:51:54.085.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterShanying Gui
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-09-10 19:11:41ID requested
12025-09-29 18:51:54announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Thyroid Cancer, ATC, PDTC, PTC, 4D-DIA
Contact List
Shanying Gui
contact affiliationHangzhou Medical College
contact emailguishanying@hotmail.com
lab head
Shanying Gui
contact affiliationHangzhou Medical College
contact emailguishanying@hotmail.com
dataset submitter
Full Dataset Link List
iProX dataset URI