PXD068127-1

PXD068127 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic analysis of hBM-MSCs and hBM-MSC-derived EVs following lipid perturbations with exogenous sphingomyelinase
Description	This experiment describes the protomic profiling of human bone marrow-dervied Mesenchymal Stromal Cells and their derived extracellular vesicles following an exogenous treatment of MSCs with neutral sphingomyelinase. Samples were ran in triplicate biological replicates with 1 MSC donor. EV samples were processed using TMTpro 16 plex labeling kit. Samples were injected and measured using a Q exactive Plus high-reslution tandem mass spectrometer.
HostingRepository	PRIDE
AnnounceDate	2025-09-05
AnnouncementXML	Submission_2025-09-05_09:44:41.838.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Daniel Shah
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-09-05 09:05:52	ID requested
⏵ 1	2025-09-05 09:44:42	announced

Publication List

10.1101/2025.08.21.671536;

10.1101/2025.08.21.671536;

Keyword List

submitter keyword: MSCs, EVs

submitter keyword: MSCs, EVs

Contact List

Edward Botchwey
contact affiliation	Professor, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University, Atlanta, Georgia, USA
contact email	edward.botchwey@bme.gatech.edu
lab head
Daniel Shah
contact affiliation	Georgia Insititute of Technology
contact email	dshah314@gatech.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD068127
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD068127

PRIDE project URI

Repository Record List

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