PXD068054-1

PXD068054 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Analyzes of PEGylation of a Heterogeneous Therapeutic Protein by Direct Mass Technology and Data Dependent Acquisition
Description	Intact mass of a heterogeneous therapeutic protein was determined by Direct Mass Technology (Orbitrap based charge detection mass spectrometry), proving mono PEGylation of the biologic. Furthermore, using multiple enzyme combinations, major PEGylation sites of the protein were mapped by finetuning instrument parameters and chromatographic conditions.
HostingRepository	MassIVE
AnnounceDate	2025-12-19
AnnouncementXML	Submission_2025-12-19_14:47:27.443.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zoltan Szabo
SpeciesList	scientific name: Recombinant Protein;
ModificationList	unknown modification
Instrument	Orbitrap Exploris 480; Q Exactive UHMR

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-09-04 04:13:04	ID requested
⏵ 1	2025-12-19 14:47:27	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Charge Detection Mass Spectrometry, Data Dependent Acquisition, PEGylation Mapping, DatasetType:Other (Characterization)

submitter keyword: Charge Detection Mass Spectrometry, Data Dependent Acquisition, PEGylation Mapping, DatasetType:Other (Characterization)

Contact List

Zoltan Szabo
contact affiliation	Thermo Fisher Scientific
contact email	zoltan.szabo@thermofisher.com
lab head
Zoltan Szabo
contact affiliation	Thermo Fisher Scientific
contact email	zoltan.szabo@thermofisher.com
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v10/MSV000099026/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v10/MSV000099026/