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PXD067888-1

PXD067888 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLi et al., Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells: CHO-pgs745 cells with 250 uM compound 1
DescriptionCHO pgs-745 cells transfected with plasmids encoding for WT or bump-and-hole-engineered human XYLT1 or XYLT2 were fed with 6AzGlc-1-phosphate precursor (250 uM) or DMSO and secretome collected. Glycoproteins were clicked with acid-cleavable biotin-alkyne, enriched on neutravidin and on-bead digested with trypsin. Peptides were desalted and run on TIMS-ToF Pro.
HostingRepositoryMassIVE
AnnounceDate2025-10-15
AnnouncementXMLSubmission_2025-10-15_05:57:37.342.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBenjamin Schumann
SpeciesList scientific name: Cricetulus griseus; common name: Chinese hamster; NCBI TaxID: 10029;
ModificationListunknown modification
InstrumenttimsTOF Pro 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-08-29 14:13:33ID requested
12025-10-15 05:57:37announced
Publication List
no publication
Keyword List
submitter keyword: Glycosaminoglycan, chemical proteomics, glycosylation, glycosyltransterase, DatasetType:Proteomics
Contact List
Benjamin Schumann
contact affiliationTUD Dresden University of Technology
contact emailbenjamin.schumann@tu-dresden.de
lab head
Benjamin Schumann
contact affiliationTUD Dresden University of Technology
contact emailbenjamin.schumann@tu-dresden.de
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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