PXD067828 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Adaptation of Burkholderia cenocepacia to low oxygen drives changes consistent with adaptation to chronic infection. |
| Description | Cystic fibrosis (CF) is characterised by chronic respiratory infections, involving opportunistic pathogens, including Burkholderia cenocepacia. The CF lung comprises hypoxic niches that drives bacterial adaptation and the adaptability of pathogens to this environment is key to their successful colonisation. We previously identified several proteins encoded on a low-oxygen activated (Lxa) locus that were significantly increased in abundance in late chronic infection B. cenocepacia isolates. However, the impact of long-term hypoxia exposure on B. cenocepacia adaptation remains unclear. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-19 |
| AnnouncementXML | Submission_2026-01-19_02:27:10.253.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ciarán Carey |
| SpeciesList | scientific name: Burkholderia cenocepacia J2315; NCBI TaxID: NEWT:216591; scientific name: Bacteria; NCBI TaxID: NCBITaxon:2; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Bruker Daltonics timsTOF series |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-08-28 04:33:22 | ID requested | |
| ⏵ 1 | 2026-01-19 02:27:10 | announced | |
Publication List
Keyword List
| submitter keyword: chronic infection, chronic lung disease., cystic fibrosis,Burkholderia cenocepacia, hypoxia, bacterial adaptation |
Contact List
| Siobhán McClean |
|---|
| contact affiliation | School of Biomedical and Biomolecular Science, University College Dublin |
| contact email | siobhan.mcclean@ucd.ie |
| lab head | |
| Ciarán Carey |
|---|
| contact affiliation | University College Dublin |
| contact email | ciaran.carey1@ucdconnect.ie |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD067828 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD067828
- Label: PRIDE project
- Name: Adaptation of Burkholderia cenocepacia to low oxygen drives changes consistent with adaptation to chronic infection.
