PXD067817-1
PXD067817 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The m6A reader IGF2BP2 promotes homologous recombination-mediated DNA repair by eliminating DNA-RNA hybrids |
| Description | The m6A reader IGF2BP2 and helicase DHX9 collaborate to remove DNA-RNA hybrids at DSB sites. This action facilitates RAD51 loading and homologous recombination, influencing cancer cell responses to DNA damage therapies. |
| HostingRepository | iProX |
| AnnounceDate | 2025-08-28 |
| AnnouncementXML | Submission_2025-08-28_01:50:25.295.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yating Sun |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ Orbitrap Elite |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-08-28 01:50:07 | ID requested | |
| ⏵ 1 | 2025-08-28 01:50:25 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: IGF2BP2, DHX9, DNA:RNA hybrids, HR |
Contact List
| Yang Li | |
|---|---|
| contact affiliation | Department of Genetics, School of Life Science, Anhui Medical University |
| contact email | liyang@ahmu.edu.cn |
| lab head | |
| Yating Sun | |
| contact affiliation | Peking University |
| contact email | 18205518861@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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