PXD067778-1

PXD067778 is an original dataset announced via ProteomeXchange.

Title	Human Lower extremity arteries LC-MS
Description	To explore potential therapeutic targets for diabetic vascular complications, we first conducted an unbiased screen at the protein level with lower extremity vessels from non-diabetic control individuals and from patients with type 2 diabetes by LC-MS/MS (liquid chromatography-tandem mass spectrometry). A total of 1093 proteins were identified by MS, of which 116 proteins were differentially expressed (false discovery rate q-value < 0.05; fold change > 1.5 or < 1/1.5) in the 3 diabetic samples (DM) compared with 3 non-diabetic controls (Non-DM), including 92 upregulated and 24 downregulated proteins.
HostingRepository	PRIDE
AnnounceDate	2025-09-05
AnnouncementXML	Submission_2025-09-04_19:02:58.569.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shuang Zhao
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-26 22:38:23	ID requested
⏵ 1	2025-09-04 19:02:58	announced

10.1126/SCITRANSLMED.ADN9216;

submitter keyword: Diabetes Human Vascular

zhao shuang
contact affiliation	Najing medical university
contact email	zhaoshuang@njmu.edu.cn
lab head
Shuang Zhao
contact affiliation	Nanjing Medical University
contact email	zhaoshuang@njmu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD067778

PRIDE project URI

• PRIDE
  1. PXD067778
     1. Label: PRIDE project
     2. Name: Human Lower extremity arteries LC-MS