PXD067767-1
PXD067767 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Quantitative N-glycoproteomic Analysis Reveals Plasma Glyco-Signatures in Sepsis |
| Description | Sepsis is a severe systemic inflammatory response that poses a significant challenge in clinical diagnosis and treatment, with early identification being crucial for improving patient outcomes. This study aimed to investigate the N-glycosylation characteristics of immunoglobulin G (IgG) in the plasma of patients with sepsis via quantitative N-glycoproteomics. Using our developed GlycoQuant strategy based on EThcD-sceHCD-MS/MS, we quantified the intact N-glycopeptides (IGPs) of IgG subclasses from 40 healthy controls (HCs) and 40 patients with sepsis (S). |
| HostingRepository | iProX |
| AnnounceDate | 2025-08-25 |
| AnnouncementXML | Submission_2025-08-26_18:40:48.524.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yong Zhang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | deaminated residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-08-26 18:33:49 | ID requested | |
| ⏵ 1 | 2025-08-26 18:40:48 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Sepsis, Immunoglobulin G, N-glycosylation, Glycopeptide, Glycoproteomics |
Contact List
| Yong Zhang | |
|---|---|
| contact affiliation | West China Hospital, Sichuan University |
| contact email | nankai1989@foxmail.com |
| lab head | |
| Yong Zhang | |
| contact affiliation | West China Hospital, Sichuan University |
| contact email | nankai1989@foxmail.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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