PXD067755 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Lactylomics for mouse MCAO/R cortex tissue |
| Description | Mice were anesthetized with 2% isoflurane (RWD, China), and a midline cervical incision was made to expose the left common carotid artery (CCA), external carotid artery (ECA), and internal carotid artery (ICA). The CCA was ligated distally, and two ligatures were placed on the ECA, one at its distal end and the other at the ECA-ICA bifurcation. A silicon-coated filament (RWD, China) was inserted into the ICA through a small incision in the ECA to occlude the middle cerebral artery. After 2 hours, the filament was removed to initiate reperfusion. Rectal temperature was maintained at 37°C throughout surgery. Sham-operated mice underwent identical procedures without filament insertion. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-07 |
| AnnouncementXML | Submission_2026-09-06_16:17:10.352.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Haipeng Wang |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | lactic acid |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-08-26 10:34:46 | ID requested | |
| ⏵ 1 | 2026-09-06 16:17:11 | announced | |
Publication List
| 10.1002/advs.202516663; |
| Duan C, Zhang R, Ding S, Feng Y, Shen T, Wang Z, Bao W, Shui K, Qin J, Chen J, Zhang M, Ren Z, Zhao D, Guo X, Ai Z, Yang X, Zhou P, Dong Z, Phosphorylation-Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia-Reperfusion. Adv Sci (Weinh), ():e16663(2026) [pubmed] |
Keyword List
| submitter keyword: ischemic stroke, reperfusion injury, MCAO/R,Lactylation, LC-MS/MS |
Contact List
| Chao Duan |
|---|
| contact affiliation | Hubei University of Medicine, Taihe Hospital |
| contact email | duanchao0803@163.com |
| lab head | |
| Haipeng Wang |
|---|
| contact affiliation | Huazhong agricultural university |
| contact email | 10115@webmail.hzau.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD067755 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD067755
- Label: PRIDE project
- Name: Lactylomics for mouse MCAO/R cortex tissue
