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PXD067738-1

PXD067738 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDextran-based T-cell expansion nanoparticles for manufacturing CAR T cells with augmented efficacy
DescriptionClick chemistry facilitates efficient antibody conjugation to NP surfaces, yet challenges persist when incubating the NPs with culturing medium. Protein corona formation in biological environments may obscure the antibodies, limiting their interactions with T cells. Hence, we conducted proteomics analysis to investigate protein corona formation on the T-Expand surface.
HostingRepositoryPRIDE
AnnounceDate2026-02-09
AnnouncementXMLSubmission_2026-02-08_16:29:20.089.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTao Zheng
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-08-26 04:37:12ID requested
12026-02-08 16:29:22announced
Publication List
Zheng T, Ramanathan K, Ormh, ø, j M, Hansen MR, Halld, ó, rsd, ó, ttir HR, Li H, Munk KK, Rodriguez-Pardo C, Friis RUW, Seder I, Heegaard PMH, Qvortrup K, Abken H, Sun Y, Hadrup SR, Dextran-based T-cell expansion nanoparticles for manufacturing CAR T cells with augmented efficacy. Nat Commun, 17(1):1103(2026) [pubmed]
10.1038/s41467-025-67868-1;
Keyword List
submitter keyword: human serum,dextran nanoparticle
Contact List
Yi Sun
contact affiliationTechnical Univeristy of Denmark, Department of Health Technology, 2800 Kongens Lyngby, Denmark
contact emailsusyi@dtu.dk
lab head
Tao Zheng
contact affiliationTechnical University of Denmark, Department of Health technology
contact emailtaozhe@dtu.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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