PXD067676-1

PXD067676 is an original dataset announced via ProteomeXchange.

Title	DIA proteomics of virgin female Schistosoma mansoni after BATT induction
Description	Schistosomiasis, a zoonotic parasitic disease caused by trematodes of the genus Schistosoma, represents a significant zoonotic parasitic disease that affects over 200 million people across 78 countries, with a substantial burden on public health systems globally. The phenomenon of male-induced sexual maturation in female schistosomes was first documented as early as 1928. However, the molecular mechanisms underlying this interaction remain poorly understood and have yet to be fully elucidated. In a significant advancement, a recent study identified a novel mechanism through which the male schistosome synthesizes a dipeptide pheromone, beta-alanyl-tryptamine (BATT), which acts as a key inducer of female reproductive development.This study aimed to answer how female schistosome initiate the sexual maturation process upon receiving BATT signals.
HostingRepository	iProX
AnnounceDate	2025-08-25
AnnouncementXML	Submission_2026-01-28_19:01:10.385.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mengjie Gu
SpeciesList	scientific name: Schistosoma mansoni; NCBI TaxID: 6183;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-24 23:33:18	ID requested
⏵ 1	2026-01-28 19:01:10	announced

Dataset with its publication pending

submitter keyword: Schistosoma mansoni, DIA proteomics, virgin, sexual maturity

Jipeng Wang
contact affiliation	Fudan University
contact email	jipengwang@fudan.edu.cn
lab head
Mengjie Gu
contact affiliation	Fudan University
contact email	121501733@qq.com
dataset submitter

iProX dataset URI