PXD067571 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic and functional profiling of suspended jejunal enteroids reveals physiological and pharmacokinetic fidelity to native intestine |
| Description | Intestinal enteroids are “mini-guts” that recapitulate essential features of the intestinal epithelium in vitro. We developed and characterized native basal-out (BO) and morphogenically everted apical-out (AO) jejunal enteroids cultured in suspension. Using quantitative proteomics, we show that these enteroids progressively adopt protein profiles closely resembling those of freshly isolated villus enterocytes and human jejunal tissue. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-21 |
| AnnouncementXML | Submission_2026-08-21_05:09:41.844.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Merve Ceylan |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-08-21 07:32:27 | ID requested | |
| ⏵ 1 | 2026-08-21 05:09:42 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: PBPK modeling, proteomics, drug metabolism, enteroids, live-cell microscopy, drug transport,Human small intestine |
Contact List
| Per Artursson |
|---|
| contact affiliation | Dr Per Artursson, Department of Pharmacy, Uppsala University, SE-75123 Uppsala, Sweden.(lab head) |
| contact email | per.artursson@uu.se |
| lab head | |
| Merve Ceylan |
|---|
| contact affiliation | PhD, Uppsala University, Department of Pharmacy, Drug Delivery |
| contact email | merve.ceylan@farmaci.uu.se |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD067571 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD067571
- Label: PRIDE project
- Name: Proteomic and functional profiling of suspended jejunal enteroids reveals physiological and pharmacokinetic fidelity to native intestine
