PXD067120-1

PXD067120 is an original dataset announced via ProteomeXchange.

Title	Role of SPOP in cardiac hypertrophy and heart failure
Description	Pressure overload-induced cardiac hypertrophy and heart failure involve profound remodeling of the myocardial proteome. To elucidate the role of the E3 adaptor protein SPOP in this process, we performed TMT-based quantitative proteomic analysis on left ventricular tissues collected four weeks after transverse aortic constriction (TAC) from Myh6-Cre control mice (n=5) and cardiac-specific SPOP knockout (cKO) mice (n=5).
HostingRepository	PRIDE
AnnounceDate	2025-08-26
AnnouncementXML	Submission_2025-08-26_09:15:38.635.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Liu jiangqi
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-08 01:38:18	ID requested
⏵ 1	2025-08-26 09:15:39	announced

Dataset with its publication pending

submitter keyword: LC-MSMS,Mouse, Heart, Tissue

Hao Wu
contact affiliation	Harbin Medical University
contact email	haowu974642@gmail.com
lab head
Liu jiangqi
contact affiliation	Harbin medical university
contact email	ljq6327@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD067120

PRIDE project URI

• PRIDE
  1. PXD067120
     1. Label: PRIDE project
     2. Name: Role of SPOP in cardiac hypertrophy and heart failure