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PXD067119-1

PXD067119 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman Plasma Discovery Proteomics
DescriptionThis study addresses this gap by conducting a direct comparison of eight platforms, representing both affinity-based and diverse mass spectrometry approaches, and covering over 13,000 proteins. By applying these platforms to the same cohort, we systematically assess their performance, identifying key differences and complementary strengths. Our findings offer valuable insights for researchers, highlighting trade-offs in coverage and their implications for biomarker discovery and clinical applications. This study serves as an essential resource, offering both technical evaluation and biological insights to support the development of novel diagnostics and therapeutics through plasma proteomics.
HostingRepositoryPRIDE
AnnounceDate2025-10-07
AnnouncementXMLSubmission_2025-10-07_02:16:59.145.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSara Ahadi
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-08-08 01:32:11ID requested
12025-10-07 02:17:00announced
Publication List
Kirsher DY, Chand S, Phong A, Nguyen B, Szoke BG, Ahadi S, Current landscape of plasma proteomics from technical innovations to biological insights and biomarker discovery. Commun Chem, 8(1):279(2025) [pubmed]
10.1038/s42004-025-01665-1;
Keyword List
submitter keyword: Human, mass spec, proteomics, targeted mass spec, plasma, affinity
Contact List
Sara Ahadi
contact affiliationAlkahest Inc.
contact emailsaraahadi@gmail.com
lab head
Sara Ahadi
contact affiliationAlkahest Inc.
contact emailsaraahadi@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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