PXD066946 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic sex determination vs osteological sex estimation – what effect do our techniques have on the way we view the people of the past? |
| Description | Amelogenin, a protein involved in the formation of enamel occurs as two isoforms, AMEL X and AMEL Y, which are encoded on the X and Y chromosome respectively. Isoform-specific peptides can be used for the determination of the chromosomal sex in ancient teeth. This strategy was used to determine the chromosomal sex of individuals from tooth material of historic New Zealand cemetery samples by mass spectrometry-based amelogenin peptide analysis. We show what can happen when osteobiographies are constructed for individuals for whom osteological sex estimation was inaccurate. We also highlight the uses of peptide analysis in identifying individuals, particularly non-adults for whom osteological sex estimation is not possible. Peptide analysis of historic New Zealand cemetery samples has helped to change our interpretations and added to our understanding of these populations. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-25 |
| AnnouncementXML | Submission_2025-11-25_11:54:33.305.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Torsten Kleffmann |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-08-04 13:00:09 | ID requested | |
| ⏵ 1 | 2025-11-25 11:54:33 | announced | |
Publication List
Keyword List
| submitter keyword: chromosomal sex determination, AMEL Y, AMEL X,Amelogenin |
Contact List
| Charlotte King |
|---|
| contact affiliation | Department of Anatomy, University of Otago, New Zealand |
| contact email | charlotte.king@otago.ac.nz |
| lab head | |
| Torsten Kleffmann |
|---|
| contact affiliation | Department of Biochemistry, University of Otago |
| contact email | torsten.kleffmann@otago.ac.nz |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD066946 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD066946
- Label: PRIDE project
- Name: Proteomic sex determination vs osteological sex estimation – what effect do our techniques have on the way we view the people of the past?
