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PXD066908-1

PXD066908 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe mass spectrometry data for the identification of eNOS-binding protein
DescriptionThe activity of endothelial nitric oxide synthase (eNOS) is regulated through intricate crosstalk among transcriptional, post-transcriptional, and post-translational modalities. Translational modification cascades and their downstream signaling relay emerge as pivotal controllers of both eNOS functionality and nitric oxide bioavailability, positioning these pathways as prime therapeutic targets. A deeper elucidation of the molecular machinery governing post-translational regulation of eNOS holds promise for developing innovative approaches to forestall endothelial dysfunction and its consequent hypertensive complications.
HostingRepositoryiProX
AnnounceDate2025-08-03
AnnouncementXMLSubmission_2026-07-21_00:13:53.398.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSijia Liang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-08-03 23:19:14ID requested
12026-07-21 00:13:53announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: eNOS degradation, Hypertension
Contact List
Sijia Liang
contact affiliationSun Yat-Sen University
contact emailliangsj5@mail.sysu.edu.cn
lab head
Sijia Liang
contact affiliationSun Yat-Sen University
contact emailliangsj5@mail.sysu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI