PXD066756 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | LFQ proteomic profiling of Streptomyces coelicolor biosynthesis pathway mutants |
| Description | Streptomyces coelicolor A3(2) is a model organism for antibiotic production at high potency. Its chromosome contains over 20 gene clusters responsible for secondary metabolite biosynthesis. This complexity of putatively competing regulatory and biosynthetic pathways can however negatively impact the yield of desired metabolite biosynthesis. Hence, a better understanding of these pathways is crucial for design of high-scale bioengineering processes. For this study proteome changes of certain S. coelicolor biosynthesis mutants were monitored. These were a double mutant with scbA protein deletion and atrA protein overexpression (∆scbA-atrAOE), as well as, an atrA protein deletion mutant (ΔatrA). These two mutants were relatively assessed against, respectively, a single mutant with scbA protein deletion (∆scbA-atrAOE vs ∆scbA-Φ) and a wild-type strain (ΔatrA vs M145). |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-02 |
| AnnouncementXML | Submission_2026-04-02_01:22:30.649.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD066756 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Michał Tracz |
| SpeciesList | scientific name: Streptomyces coelicolor A3(2); NCBI TaxID: NEWT:100226; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Synapt XS |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-07-30 05:39:37 | ID requested | |
| ⏵ 1 | 2026-04-02 01:22:31 | announced | |
Publication List
Keyword List
Contact List
| dr Michał |
|---|
| contact affiliation | Laboratory of Mass Spectometry |
| contact email | michal.tracz2@uwr.edu.pl |
| lab head | |
| Michał Tracz |
|---|
| contact affiliation | Laboratory of Mass Spectrometry, Faculty of Biotechnology, University of Wroclaw |
| contact email | michal.tracz2@uwr.edu.pl |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD066756 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD066756
- Label: PRIDE project
- Name: LFQ proteomic profiling of Streptomyces coelicolor biosynthesis pathway mutants
