PXD066664 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Oxidative Stress and Metabolic Plasticity of NOX-2 KO mice Hematopoitic Stem Cells Homeostasis Proteomics Profile |
| Description | We investigated the contribution of NOX-2 to redox balance, mitochondrial respiration, and glycolytic compensation in lineage-negative Sca-1⁺c-Kit⁺ (SKL) bone marrow stem cells from wild-type (WT) and NOX-2 knockout (NOX2-KO) mice. Proteomic profiling identified differentially expressed proteins involved in hypoxic response, glycolysis, and oxidative stress adaptation between WT and NOX2-KO SKL cells. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-12-03 |
| AnnouncementXML | Submission_2025-12-03_13:11:12.581.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Kannathasan Thetchinamoorthy |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | compact; 6520A Quadrupole Time-of-Flight LC/MS |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-07-28 08:05:42 | ID requested | |
| ⏵ 1 | 2025-12-03 13:11:13 | announced | |
Publication List
Keyword List
| submitter keyword: Hematopoitic Stem Cells, NOX-2 KO,NOX-2, Proteomics, Metabolic Plasticity |
Contact List
| Kannathasan Thetchinamoorthy |
|---|
| contact affiliation | Laboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland |
| contact email | kannathasan.thetchinamoorthy@wum.edu.pl |
| lab head | |
| Kannathasan Thetchinamoorthy |
|---|
| contact affiliation | Laboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw |
| contact email | kannathasan.thetchinamoorthy@wum.edu.pl |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD066664 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD066664
- Label: PRIDE project
- Name: Oxidative Stress and Metabolic Plasticity of NOX-2 KO mice Hematopoitic Stem Cells Homeostasis Proteomics Profile
