PXD066508 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | A novel blood biomarker for plastic ingestion in fledgling Procellariiform seabirds |
| Description | Plastic ingestion is a well-established threat to wildlife, inducing a series of lethal and sublethal physiological consequences. Yet monitoring the ongoing sublethal implications of plastic exposure in live wild populations remains challenging, making the development of a minimally invasive biomarker for plastic exposure a longstanding priority. In this study, we investigate the application of proteomic signatures identified in de Jersey, et al. (1) as a biomarker approach and validate across Procellariform seabird species of varying levels of plastic ingestion. Utilising data-independent mass spectrometry on plasma, we developed a consistent and reliably detectable biomarker signature with 96% accuracy for plastic ingestion from as little as 0.5 g of ingested plastic. Rather than relying on a single protein prone to biological and technical variability, our pathway-level approach integrates functionally related proteins, capturing consistent and conserved responses to plastic ingestion across species. These include elevated evidence of cell lysis, compromised stomach permeability and fibrosis, and a decrease in secreted proteins. The detected physiological patterns are aligned with emerging models of plastic-induced pathology and diseases, such as plasticosis. Our findings establish a foundation for a non-lethal, scalable tool capable of diagnosing plastic exposure across seabird taxa, with potential applications in broader ecological monitoring and conservation programs. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-29 |
| AnnouncementXML | Submission_2026-06-28_17:59:03.442.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Richard Wilson |
| SpeciesList | scientific name: Fulmarus glacialis; NCBI TaxID: NEWT:30455; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-07-24 00:48:01 | ID requested | |
| ⏵ 1 | 2026-06-28 17:59:03 | announced | |
Publication List
Keyword List
| submitter keyword: Proteomics |
| Shearwater |
| Sublethal,Environmental toxicology |
| Microplastics |
| Petrel |
Contact List
| Dr Richard Wilson |
|---|
| contact affiliation | Proteomics facility, Central Science Laboratory, University of Tasmania |
| contact email | richard.wilson@utas.edu.au |
| lab head | |
| Richard Wilson |
|---|
| contact affiliation | University of Tasmania |
| contact email | richard.wilson@utas.edu.au |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD066508 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD066508
- Label: PRIDE project
- Name: A novel blood biomarker for plastic ingestion in fledgling Procellariiform seabirds
