PXD066139-2

PXD066139 is an original dataset announced via ProteomeXchange.

Title	Cross-tissue deep profiling of redox proteome in obese mice
Description	Cellular redox state, the balance between oxidation and reduction, is precisely regulated through cysteine thiol modification. In this study, we developed a novel method, in conjunction with directed data-independent acquisition (dDIA) for identifying and quantifying a substantial number of sulfhydryl sites. Our method provided a valuable tool for large-scale investigations of redox regulation and oxidative stress in disease.
HostingRepository	iProX
AnnounceDate	2025-07-15
AnnouncementXML	Submission_2026-03-04_23:09:08.021.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jinlong Wang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-07-15 00:55:57	ID requested
1	2025-07-15 00:56:16	announced
⏵ 2	2026-03-04 23:09:08	announced	2026-03-05: Add info.

Liu J, Jiang X, Li Y, Shen L, Li X, Wang X, Wang J, Cross-tissue deep profiling of redox proteome in obese mice using enhanced resin-assisted capture and data-independent acquisition. Redox Biol, 90():104056(2026) [pubmed]

submitter keyword: Redox proteome, mouse, obese, DIA, cross-tissue

Jinlong Wang
contact affiliation	Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Chinese Academy of Sciences
contact email	jinlongwang@ucas.ac.cn
lab head
Jinlong Wang
contact affiliation	Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Chinese Academy of Sciences
contact email	jinlongwang@ucas.ac.cn
dataset submitter

iProX dataset URI