PXD065984-1

PXD065984 is an original dataset announced via ProteomeXchange.

Title	proteomic analysis reveals the toxin diversity of the spider Macrothele bannaensis
Description	pider toxins are an important and abundant source of bioactive compounds and represent molecular candidates for the development of novel compounds for use in medicine and agriculture. Despite the vast diversity of spider species, only a small fraction of them have been studied in detail regarding venom chemistry. Macrothele bannaensis, a spider belonging to the family Macrotheleidae, is widely distributed in the Xishuangbanna region of Yunnan, China, and serves as an important natural enemy of agricultural pests. However, there is a lack of research on the composition of its venom. Proteomic analysis identified 98 venom toxins, which were preliminarily classified into three categories based on annotation: DRPs (n=12), proteins and enzymes (n=23), and uncharacterized toxins (n=63).
HostingRepository	iProX
AnnounceDate	2025-07-09
AnnouncementXML	Submission_2025-11-30_23:10:31.902.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yulin Zheng
SpeciesList	scientific name: Macrothele; NCBI TaxID: 93712;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-07-09 22:44:04	ID requested
⏵ 1	2025-11-30 23:10:32	announced

Zheng Y, Yin W, Tembrock LR, Yang M, Zhang M, Zhao Y, Yang Z, Integrative transcriptomic and proteomic analysis reveals the toxin diversity of the spider Macrothele bannaensis. Int J Biol Macromol, 322(Pt 2):146740(2025) [pubmed]

submitter keyword: spider, Macrothele bannaensis, toxin diversity

Zizhong Yang
contact affiliation	College of Pharmacy, Dali University
contact email	yangzzh69@163.com
lab head
Yulin Zheng
contact affiliation	College of Pharmacy, Dali University
contact email	18275457350@163.com
dataset submitter

iProX dataset URI